Endocrine Abstracts

Objective: To assess the quality of life, the presence and severity of depressive symptoms in patients with diabetes combined with gastroparesis and without itMethods: Forty three patients with diabetes were included in the study. The presence and severity of gastrointestinal symptoms, as well as the intensity and frequency of symptoms over the last 2 weeks, were measured with the Patient Assessment of the upper gastrointestinal symptom severity index (P...

Background: Was performed an open study in 2 parallel groups to compare the efficacy and safety of dulaglutide and liraglutide in combination with Metformin in patients with type 2 diabetes mellitus.Methods: Thirty-two patients (13 men and 19 women) with type 2 diabetes mellitus with unsatisfactory glycemic control on Metformin monotherapy were examined. The median age was 52 [44; 61] years old, the duration of diabetes was 4.6 [2,5; 9,0] years, median o...

Objectives: Estimate the prevalence of of cardiovascular symptoms, to identify the main changes in echocardiography at Graves disease (GD) and their dynamic during treatment.Methods: Investigated 86 patients with GD. The functional class (FC) chronic heart failure (CHF) was determined according to the New York Heart Association (NYHA). All patients underwent echocardiography before treatment and after 3 months of euthyroid state.Re...

The research goal was to study serum concentration of immunoregulatory cytokines (IL-1ß, IL-6ß, IL-8ß, IL-10ß) in 80 patients with manifest hypothyroidism at the age of 21–50. 48 patients suffering from chronic autoimmune hypothyroidism and 32 patients with postoperative hypothyroidism were examined. It was revealed that autoimmune hypothyroidism effects balance disturbance of cytokine-producing activity Th1 and Th2 types, this plays an important role ...